A population-scale single-nucleus study of 287 human skeletal muscle biopsies maps cell-type-specific eQTLs and caQTLs that ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Human, chimpanzee and gorilla brain organoids reveal how shared genes operate differently, offering clues to stem-cell shape ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. Alternative splicing—the way cells edit gene messages—forms a second, independent layer of ...

Some genetic diseases leave cells without a crucial protein. One possible treatment is to persuade genes already inside those ...

An innovative CRISPR-Cas12f-based activator system may hold significant potential in the future of gene therapy and biological research, suggest researchers of a new study. The study highlights the ...

Scientists can now edit genes in precise locations deep in the brain and body without the use of invasive surgery or implants ...

Researchers say gene switches currently offer limited temporal and spatial precision and can also have adverse effects. Now, a recent study, “Electromagnetic field-inducible in vivo gene switch for ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

A laboratory proof of concept shows that engineered plants can release a noncanonical amino acid that activates selected genes in nearby engineered bacteria.