Nature

An unexpected function of a cell-cycle enzyme might explain the toxic effects of its inhibitors

A previously unknown mechanism required for cells to start proliferating has been identified. A combination of mathematical modelling and cell-based experiments shows that the enzyme WEE1 switches off ...
BIOENGINEER

WEE1 kinase guards quiescent cells’ path back into the cell cycle

A Nature study shows that the WEE1 kinase promotes cell cycle re-entry from quiescence by phosphorylating CDH1 to inhibit the ...
BIOENGINEER

Public-data reanalysis identifies cell-cycle signal in sinonasal cancer

A public-data reanalysis identified broad tumor-normal gene-expression changes in sinonasal squamous cell carcinoma and ...
Medical Xpress

Cellular senescence: When growth stimulation meets cell cycle arrest

A new review paper titled "Cellular senescence: when growth stimulation meets cell cycle arrest" has been published in Aging. In this review, researcher Mikhail V. Blagosklonny, M.D., Ph.D., from ...
EurekAlert!

Aging | Cellular senescence: when growth stimulation meets cell cycle arrest

BUFFALO, NY- March 2, 2023 – Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) published a new review paper in Volume 15, Issue 4, entitled, “Cellular senescence ...